About Meniere’s Disease

Meniere's disease is a disorder of the inner ear that affects balance and hearing. The most common symptoms include vertigo (dizziness), hearing loss, tinnitus (ringing in the ear), and a feeling of fullness in the ear. In the early stages, Meniere's disease is usually unilateral (occurring on one side). There is no predominance of right or left ear. Meniere's disease is also called idiopathic endolymphatic hydrops. The cause of Meniere's disease is unknown. It was first described by a French physician, Dr. Prosper Meniere, in 1861.

There have been many hypotheses regarding the underlying causes of Meniere's disease since its first description in 1861, including:

  • Genetic predisposition - Approximately 5%-20% of individuals diagnosed with Meniere's disease report that a family member has or had Meniere's disease or similar symptoms. In addition, chromosomal studies appear to be making progress in identifying certain genetic markers in individuals diagnosed with Meniere's disease.

  • Allergies - Individuals with Meniere's disease report higher rates of allergies than people not affected with Meniere's, and some studies have shown higher rates of serum immune markers in individuals with Meniere's disease than those without. In addition, studies have shown that individuals with allergies and Meniere's disease report an improvement in the severity and duration of their Meniere's attacks when treated with immunotherapy and/or dietary adjustments.

  • Migraine headaches - There appears to be an association between Meniere's disease and migraine headaches. Reports in one study indicated that the prevalence of migraine in individuals with Meniere's disease was 56%, compared to 10% among the general population; and that 45% of individuals with Meniere's disease always experienced at least one symptom of migraine headaches (e.g., aura, or an aversion to light) during Meniere's attacks.

  • Otosclerosis - Some individuals with otosclerosis (a rare condition of formation of spongy bone around the stapes) have symptoms of Meniere's disease. It is thought that otosclerotic formations may cause malformation in the endolymphatic sac or may change the chemical properties of the perilymphatic and endolymphatic fluid.

Although the exact underlying cause of Meniere's disease is not clear, it has been associated with an excess of endolymphatic fluid within the cochlear duct and vestibular system - a condition known as -endylymphatic hydrops-. It is also not clear whether endolymphatic hydrops is the cause or the result of Meniere's disease, since there are known cases of individuals with endolymphatic hydrops who otherwise have no symptoms of Meniere's disease.

While Meniere's disease is the second most common cause of vertigo in the U.S., it is listed in the National Organization of Rare Diseases (NORD) database as a rare disease. Information regarding the precise incidence and prevalence of Meniere's disease is scarce, but some estimates range from 15 to 150 cases per 100,000 people.

Additional important statistics about Meniere's disease include:

  • Meniere's disease most often affects adults between the ages of 40 and 60.
  • Approximately 40,000 new cases of Meniere's disease are diagnosed annually in the U.S.
  • Approximately 3% of patients diagnosed with Meniere's disease are children.
  • Male-to-female ratio ranges from equal to a slight preponderance of females over males. Some women report improvement of symptoms following pregnancy.
  • Although most cases of Meniere's disease are usually unilateral (occurring on one side only), up to 10% of individuals have bilateral Meniere's disease affecting both ears at the time of diagnosis. Over the course of time, approximately 50% of individuals also develop symptoms in the opposite ear.

There is no consistent pattern for the progression of Meniere's disease. It may or may not be progressive. For many people, vertigo attacks occur for the first two to three years, during which vertigo can usually be controlled by medication. In approximately one out of four individuals, progression of vertigo continues despite medical treatment and reaches a point where the vertigo is refractory (not responsive) to treatment and is incapacitating. At that point, individuals may be considered candidates for surgery.

The diagnosis of Meniere's disease is based on:

  • History and physical examination
  • Laboratory testing
  • Audiometric (hearing) studies
  • Balance tests
  • Imaging studies

The diagnosis of Meniere's disease can be challenging because there are many other conditions that can present with similar clinical symptoms. Some of the conditions that need to be considered in the differential diagnosis of Meniere's disease include:

  • Benign paroxysmal positional vertigo (BPPV) - Episodes of short-lasting vertigo that are usually brought on by movement and are not associated with hearing loss or tinnitus.
  • Acoustic neuroma - A slow-growing tumor of the auditory nerve that can cause symptoms similar to Meniere's disease.
  • Vestibular neuritis - A viral inflammation of the vestibular nerve that causes vertigo.
  • Labyrinthitis - Inflammation of the labyrinth that causes dizziness, imbalance, and temporary hearing loss.
  • Acute hearing loss - Hearing loss that could be idiopathic (for no observable reason).
  • Migraine headaches - Severe headaches that can cause dizziness.

Although currently there is no cure for Meniere's disease, there are many treatments available to manage individual symptoms, especially vertigo, the single symptom that people report as being the most disruptive in their daily lives. The goals of treatment are to relieve the symptoms, to prevent or minimize vertigo attacks, and to help people suffering from vertigo achieve as little disruption of their daily activities as possible. Psychological support is beneficial as it helps individuals with Meniere's disease learn to better cope with symptoms and their impact on quality of life.

In general, the treatment options for Meniere's disease include:

  • Restriction of dietary salt intake
  • Medications to prevent and treat vertigo
  • Intratympanic injections of steroids or gentamicin
  • Surgical therapy for patients with unremitting attacks of vertigo that cannot be controlled with medications.

The prognosis of Meniere's disease varies significantly from patient to patient. There is no cure for the condition, only symptom management. Meniere's disease usually affects only one ear and estimates vary widely regarding the number of people who develop bilateral Meniere's disease. Surgery is performed in up to 10% of patients with Meniere's disease, typically those who do not respond to more conservative treatments and who continue to experience disabling episodes of vertigo.


The Medifocus Guidebook on Meniere’s Disease is a unique, comprehensive patient education resource that contains vital information about Meniere’s Disease that you won't find anywhere else in a single resource. The Guidebook will answer many of your questions about this condition that your healthcare provider may not have the time to answer. To learn more about the Guidebook, please click here
 

About the Medifocus Guidebook on Meniere’s Disease

If you or a loved one has been diagnosed with Meniere’s Disease, it's important to learn as much as you possibly can about this condition so that you can make informed decisions about your treatment.

The Medifocus Guidebook on Meniere’s Disease is a unique and comprehensive patient education resource that contains vital information about Meniere’s Disease that you won't find anywhere else in a single source. Available both as a Soft-Cover Book and as an E-Book (PDF), the Guidebook will answer many of your questions about Meniere’s Disease, including:

  • The causes and risk factors for Meniere’s Disease.
  • The clinical signs and symptoms.
  • The diagnostic tests and procedures that are necessary to confirm the diagnosis of Meniere’s Disease.
  • The standard treatments and the treatment options currently available for the management of Meniere’s Disease.
  • The impact of Meniere’s Disease on quality of life.
  • The latest clinical and research advances for Meniere’s Disease as reported in credible, trustworthy medical journals.
  • A directory of doctors and medical centers that have special interest and clinical expertise in the management of patients with Meniere’s Disease.
  • A listing of organizations where patients can seek additional information, services, and support.

Whether you've been newly diagnosed with Meniere’s Disease or have suffered with it for several years, the Medifocus Guidebook on Meniere’s Disease can serve as a valuable resource to help you better understand and cope with this condition. When you purchase your copy of either the Soft-Cover Book or the E-Book (PDF), you will also receive Free Updates for one-year.

Thousands of satisfied customers have purchased the Medifocus Guidebook on Meniere’s Disease for themselves, a loved one, and even their healthcare provider. Their Testimonials are a tribute to the quality of the work product that our editorial staff has created. With a customer-satisfaction rating of over 98%, we're so confident that you will be satisfied with your purchase that we offer an iron-clad Risk-Free Satisfaction Guarantee. To learn more about the content, please download a Free Preview of the Guidebook that will enable you to review an abbreviated version of the individual sections.

Testimonials

I am very grateful for your MediFocus Guidebook on Meniere's Disease. It gave me the tools that I needed to research Meniere's. By educating myself about this condition, I feel that I am able to participate in my course of future medical procedures. It wasn't left up to the doctor alone to do what he thought was best. I have a say in what happens to me. Thanks to your Guidebook, now I am an "informed" patient.
S.R.
Tiffin, Ohio
Thanks for a chance to say a few words about your MediFocus Guidebook. When unexplained illness hit me, I didn't know what it was or what to ask my doctor. Then I purchased your Guidebook and that made all the difference. When I arrived with a list of pointed questions, the doctor spent more time with me than before and I felt comfortable understanding the diagnosis and treatment. Thanks for understanding what I was up against... it has helped a lot.
D.S.
Prescott, Arizona
It is great to have serious health issues explained in an easy to understand format. When you are ill, it is overwhelming when you trying to search for information about your illness. Medifocus helps you find the important information regarding your issues and the latest research and discussions by the medical profession. I am enjoying my Guidebook.
E.P.
Ft. Bragg, California
Thanks for the wonderful MediFocus Guidebook. The more familiar I've become with it, the less it scares me to know that I have this condition. It is comforting to know that there is so much research ongoing even though there is not a cure just yet. Many thanks for your Guidebook?one person could never have compiled all of these sources together alone.
J.Y.B.
Jacksonville, Florida
I found the Guidebook very comprehensive and written in a professional and clear style. I would recommend your books to anyone who has a problem and needs to go to a doctor. Trusting your health issues in the hands of a doctor who may or may not be good or professional is no longer acceptable. I found that my father-in-law's doctor does not actually know about many of the studies described in the book even though he is considered to be one of the "specialists" in this domain.
M.S.
Sydney, Australia
The Medifocus Guidebook is helping me to understand my condition much more in-depth than before. My doctor described the disease in medically technical terms only. I have used my Guidebook to access a variety of information sources and now have not only a better understanding of my ailment, but also several treatments have been revealed which I did not previously know about.
J.H.
Nashville, Tennessee

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